Supporting Biotech, Biopharma, and Gene Therapy with Integrated, High-Quality Cell Banking
Accelevir’s cell banking services support your therapeutic development lifecycle from early discovery through clinical trial readiness. Whether you need a robust Master Cell Bank (MCB), a GMP-compliant Working Cell Bank (WCB), or highly viable cryopreserved PBMCs, Accelevir combines scientific rigor, regulatory excellence, and deep cellular expertise to ensure your cell assets are production-ready.
We offer:
- CLIA-certified and quality-controlled facilities
- Experience in mammalian, microbial, and viral systems
- Integration with flow cytometry, bioanalytical, and molecular diagnostic services
What Is Cell Banking?
Cell banking involves the creation, storage, and management of homogeneous, validated cell populations for consistent use in research, bioproduction, and clinical trials. Accelevir supports all major bank types:
- Master Cell Bank (MCB)
- Working Cell Bank (WCB)
- Research Cell Bank (RCB)
- End-of-Production Cell Bank (EoPCB)
- Virus Seed and Challenge Virus Banks
These services underpin biologics manufacturing, gene therapy, immunotherapy, and vaccine development.
Our Cell Banking Capabilities
Accelevir offers:
- GMP-like processes within CLIA-certified workflows
- Cryopreserved PBMC processing from whole blood and leukopaks
- Density gradient centrifugation (Ficoll-Paque, Percoll, Lymphoprep)
- Automated aliquoting and RoboSep™-based cell isolation
- Long-term vapor-phase LN2 and -70°C storage
Supported Cell Lines and Systems
We handle a wide range of cell systems, including:
- Mammalian: CHO, HEK293, Vero
- Insect: SF-9, baculovirus-based lines
- Microbial: E. coli, yeast, anaerobes
- PBMCs from whole blood or leukopaks
- Suspension and adherent cell lines
Cell Bank Manufacturing Process
From qualification through cryopreservation, we deliver end-to-end control:
- Pre-seed testing and viability assessment
- Test run simulation
- Cell expansion and harvesting
- Cryopreservation and vialing (up to 1,000 vials/run)
- Integrated QC and custom protocols
Cleanroom & Facility Standards
Our operations align with GMP and ICH standards:
- CLIA-certified laboratory environment
- ISO 6–8 cleanroom workflows
- Temperature-controlled cryostorage
- Biosafety and QA oversight
Cell Line Characterization & Quality Testing
To ensure the reliability of your cell banks, we offer:
- Viability and sterility testing
- Mycoplasma detection
- Genetic stability and identity assays
- Digital PCR and flow cytometry analysis
- Custom testing plans aligned to ICH Q5A/B/D
Storage and Distribution Services
We support:
- Short- and long-term storage in secure, monitored environments
- Global logistics, customs-ready documentation, and chain-of-custody tracking
Regulatory & Quality Compliance
- GMP-like practices under a robust Quality Management System
- Adherence to FDA and EMA-aligned standards
- Independent audits and client quality assessments available
End-to-End Project Support
We offer personalized support throughout the cell bank lifecycle:
- Technical consultation and planning
- Cell bank mapping and project timelines
- Coordination with immunogenicity, cytotoxicity, and NGS services
Why Accelevir?
- Decades of immunology and virology expertise
- Integrated services spanning bioanalytical assays, PCR, and comparator testing
- Scientist-led approach with dedicated project management
- Flow cytometry, ELISpot, and qPCR integration for downstream use
- Rapid turnaround and high reproducibility
Book Your Cell Banking Consultation Today
Ready to streamline your cell banking process and enhance your biologics pipeline? Connect with our team to discuss your requirements.
Resources
Frequently Asked Questions
Why is cell banking important?
It ensures reproducibility and scalability of biologic and gene therapy products, supporting regulatory and manufacturing success.
What’s the difference between MCB and WCB?
MCBs serve as the primary repository; WCBs are derived from them and used in production.
What testing is required for GMP-compliant banks?
Viability, sterility, mycoplasma, genetic identity/stability, and biosafety per ICH guidance.
Can Accelevir handle PBMC cryopreservation?
Yes, we specialize in PBMC processing, isolation, and cryopreservation with validated SOPs.