Dendritic Cell Activation Assays for Vaccine and Immunotherapy Development
Dendritic cells (DCs) are central to initiating adaptive immune responses. Accelevir provides dendritic cell activation assays to evaluate antigen presentation, costimulatory molecule expression, and cytokine production in response to vaccines, gene therapies, or biologics.
Technical Capabilities:
- Flow cytometry for CD80, CD86, HLA-DR, and maturation markers.
- Cytokine secretion analysis via Luminex or ELISA.
- Allogeneic mixed lymphocyte reaction (MLR) to assess T-cell activation capacity.
- GLP-validated DC activation workflows for regulatory vaccine testing.
Why Partner with Accelevir:
- Specialized in DC activation profiling for AAV, mRNA, and oncolytic virus platforms.
- Ability to combine molecular readouts with functional immune assays.