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Targeted Short- & Long-Read Sequencing

Accelevir provides targeted short-read NGS and long-read sequencing for therapeutic vector characterization, CRISPR off-target mapping, and AAV genome integrity analysis. Our platforms combine base-level accuracy with the ability to resolve large structural variations.

Capabilities:

  • Short-read NGS for variant detection, quantification, and allele frequency analysis.
  • Long-read sequencing for structural variant mapping, integration site profiling, and vector genome stability.
  • Custom target enrichment to boost sensitivity in low-abundance samples.
  • Bioinformatics pipelines for viral vectors, edited genomes, and pathogen sequencing.

Applications:

  • On/off-target CRISPR sequencing.
  • AAV genome integrity QC.
  • Viral diversity and quasispecies analysis.
  • Integration site mapping for safety assessment.
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